Collaborations

Cardio3 BioSciences enjoys collaborations with the following centers of excellence:

Academic and clinical collaborations

The Company has core relationships and collaborations with Mayo Clinic and Cardiovascular Centre Aalst.

Mayo Clinic, Rochester (MN), USA: Since 2007 Cardio3 BioSciences has had a core academic, research and licence collaboration with Mayo Foundation for Medical Education and Research (“Mayo Clinic”). Mayo Clinic is ranked as the number 2 hospital in the US second to John Hopkins, and number 2 in Heart and Heart Surgery, second to Cleveland Clinic.

The Company's current relationship with Mayo Clinic is essentially based on the Technology License Agreement, through which the Company acquired at arms’ length rights to the majority of its current intellectual property portfolio and which has created a long-term research relationship with Mayo Clinic.

Cardiovascular Center, Aalst, Belgium: The department of cardiology of the Cardiovascular Centre of the Onze-Lieve-Vrouw hospital of Aalst provides scientific and clinical guidance to the Company in the areas of clinical expertise, protocol design, review and interpretation of data as well as scientific publications.

Industrial collaborations

The Company has entered into industrial collaborations with the following companies:

• Artelis: Cardio3 Biosciences is working with Artelis on the optimisation of the manufacturing processes with a view to reducing the cost of the product. Artelis is a technology company that provides disposable bioprocess solutions, from optimisation to intensification.

• Creganna Contract Design Services (CDDS): Cardio3 Biosciences has teamed up with Creganna for the development of C-Cath. CDDS is part of Creganna Corp, a global player in the medical device field with expertise in catheters and needles. CDDS provides assistance with device development, engineering and manufacturing activities.